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This biosimilar antibody shares variable regions with therapeutic antibody Gevokizumab, ideal for research. Gevokizumab, a fully humanized monoclonal antibody, binds human IL-1β (a monocyte-derived pro-inflammatory cytokine). It targets a unique IL-1β epitope, reducing IL-1-receptor binding to neutralize IL-1β, used in preclinical research (in vitro/in vivo) for type 1 diabetes, inflammation, RA, cardiovascular biology, and cancer immunotherapy.
| Product Name | BioSIM anti-Human IL-1b Antibody (Gevokizumab Biosimilar), Research Grade |
| Size | 1mg/5mg |
| Isotype | / |
| Target | IL-1b |
| Other Names | XOMA052, CAS: 1129435-60-4 |
| CAS | 1129435-60-4 |
| Reactivity | Human |
| Host Species | Humanized |
| Background | This biosimilar antibody shares variable regions with therapeutic antibody Gevokizumab, ideal for research. Gevokizumab, a fully humanized monoclonal antibody, binds human IL-1β (a monocyte-derived pro-inflammatory cytokine). It targets a unique IL-1β epitope, reducing IL-1-receptor binding to neutralize IL-1β, used in preclinical research (in vitro/in vivo) for type 1 diabetes, inflammation, RA, cardiovascular biology, and cancer immunotherapy. |
| Applications | ELISA, FACS, Functional assay, Research in vivo |
| Purification | Protein A/G |
| Storage | To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Shipping | 2-8°C with blue ice |
| Concentration | Lot specific, generally ≥ 5.0 mg/ml |
| Shelf Life | 12 months from the date of receipt if stored as recommended |
| Formulation | PBS, pH 7.4, contains no stabilizers or preservatives |
| Sterility | 0.2 μM filtered |
| Endotoxin | ≤ 1.0 EU/mg |
| Purity | 99% |
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