Home > Products > Biosimilars

BioSIM anti-Human Amyloid Beta/Aβ Antibody (Donanemab Biosimilar), Research Grade

Catalog: SIM0780
Cost advantage to: SIM0048
Product Details Specifications Application References Related Products

Product Details

This non-therapeutic biosimilar antibody shares the same variable regions as therapeutic Donanemab, ideal for research. Donanemab, a humanized IgG1κ anti-human APP antibody, specifically binds Aβ42 (linked to Alzheimer’s disease, AD) and clears plaques via microglial phagocytosis in mice (no microhemorrhages). It’s used in in vitro/in vivo studies on AD and Down syndrome.
 

Specifications

Product Name BioSIM anti-Human Amyloid Beta/Aβ Antibody (Donanemab Biosimilar), Research Grade
Size 1mg/5mg
Isotype /
Target Amyloid Beta/Aβ
Other Names LY3002813, CAS: 1931944-80-7
CAS 1931944-80-7
Reactivity Human
Host Species Humanized
Background This non-therapeutic biosimilar antibody shares the same variable regions as therapeutic Donanemab, ideal for research. Donanemab, a humanized IgG1κ anti-human APP antibody, specifically binds Aβ42 (linked to Alzheimer’s disease, AD) and clears plaques via microglial phagocytosis in mice (no microhemorrhages). It’s used in in vitro/in vivo studies on AD and Down syndrome.
Applications ELISA, FACS, Functional assay, Research in vivo
Purification Protein A/G
Storage To ensure appropriate storage, Please avoid repeated freeze thaw cycles. Keep the product at 4°C for short-term needs (1–2 weeks); Store at -20°C for up to 12 months.  For long-term storage, store at -80°C.
Shipping 2-8°C with blue ice
Concentration Lot specific, generally ≥ 5.0 mg/ml
Shelf Life 12 months from the date of receipt if stored as recommended
Formulation PBS, pH 7.4, contains no stabilizers or preservatives
Sterility 0.2 μM filtered
Endotoxin ≤ 1.0 EU/mg
Purity 99%

Application References

Related Products